Two people are in a critical condition following the shooting on Canal Street in the early hours of Sunday.
One person has been detained following the incident but no arrests have been made, police said.
New Orleans Police Department tweeted: “#NOPD is investigating a shooting in the 700 block of Canal Street. Initial reports showing multiple victims. A suspect has been apprehended near the scene. No further details at this time.”
In a later tweet, they added: “An individual was detained near the scene. However, their possible involvement in this incident remains under investigation. No arrests have been made at this time. Investigation remains ongoing. #NOPDAlert.”
More to follow.